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We strongly believe that the prior negative evidence is so abundant that we have the ethical obligation to consider and use this methodology in the analysis of any new therapy for severe sepsis.
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During the last 10 years, surgically implanted devices for continuous telemetric registrations of heart rate and blood pressure have been used by us, who may be the only group using this methodology in the goat.
If we had used this methodology in past years, we would have repeatedly overspent on our litigation legal aid budget".
The results show a marked improvement using this methodology in relation to the classic GP and international code procedures.
Our group has recently used this methodology in similar and other systems of industrial interest [17, 18, 19].
Recent research using this methodology in the cultural heritage field includes the determination of Sibyks [17], rock art [18, 19], bronzes [20] and miniatures [21].
Using this methodology in a model tumor system, murine Tregs designed to express the tyrosinase TCR effectively blocked antigen-specific effector T cell (Teff) activity as determined by tumor cell growth and luciferase reporter-based imaging.
We have used this methodology in previous studies of this nature [ 11, 12].
We therefore used this methodology in order to describe the focal changes of brain activity.
However, one of the main strengths of the study was the novelty of using this methodology in participants with obesity, encouraging its use in consolidating clinical practice.
It seems likely that large-scale genetic screens using this methodology in zebrafish will be forthcoming in the near future, complementing what has been done using ENU screens.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com