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Using this crystal structure, we have developed an in silico drug docking model in order to study the binding of ML and other anthelmintic drugs to Cel-Pgp-1.
Here we used this crystal structure as a template to assess the likely positioning of the ectoine and 2-oxoglutarate ligands within the active site by structural comparison, molecular dynamics simulations, and site-directed mutagenesis.
Using this crystal structure as a template, we have provided a complete model of the human cofactor in solution (19).
A three-dimensional structure for human NAT1 has recently been released, and we have used this crystal structure to generate a model of the mouse Nat2 structure.
In this paper, we use the crystal structures of the nucleosome core particle, B-DNA and the globular domain of H5 linker histone to build the first all-atom model of compact chromatin fibers.
Use the crystal palace for your Hogwarts.
We constructed a 3-D model of this protein using the crystal structure of the highly homologous Medicago sativa caffeic acid/5-hydroxyferulic acid O-methyltransferase (MsCOMT) as a template with the aim of proposing a mechanism for multiple methyl transfer reactions in wheat.
Using this method, crystals (>1 cm3) of HMX were grown with temperature lowering at the rate of 0.05 K hr−1 in the range 318 - 291 K.
The test set of reflections used for cross validation corresponded to the one used in previous refinements of this crystal form of AfUGM.
According to the nomenclature used by Koini et al. this crystal orientation will be labeled type A. Furthermore, we observe peaks originating from 6T crystals oriented with their {100} net planes parallel to the substrate surface (type S).
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CEO of Professional Science Editing for Scientists @ prosciediting.com