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If the LEO and FEO use the same molecular mechanisms to keep time, then they should respond similarly to biochemical and genetic alterations of the clock.
Initially, the PCL forms in a similar way to a centriole, as they both use the same molecular pathways.
Thus, it is easily imaginable that selectin ligand interactions between endothelia and tumour cells use the same molecular mechanisms as leukocytes do.
Although work with BRD4 inhibitors suggests that multiple MLL-FPs use the same molecular pathway for leukemogenesis (Dawson et al., 2011; Zuber et al., 2011), this cannot explain the fact that MLL-AF4, MLL-AF9, and MLL-ENL produce different leukemias even when expressed in the same cell type (Drynan et al., 2005; Metzler et al., 2006).
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The researchers linked the iron particles to genetically engineered proteins called monoclonal antibodies, designed to bind to PSA using the same molecular handle.
In recent years, the concept of "theranostics," the effective combination of both imaging and treatment with radiopharmaceuticals using the same molecular target, has been successfully applied to imaging and treatment of castration-resistant prostate cancer (CRPC).
The developmental expression of these signalling systems, along with that of many metazoan-specific transcription factor families [23], indicates that the last common ancestor to all living metazoans already possessed the regulatory capacity to form complex body plans, using the same molecular components as animals living over 550 million years later [49].
C. rodentium is a natural mouse pathogen that is related to, and uses the same molecular mechanisms of type III secretion and attaching and effacing lesions as human EPEC and EHEC, to colonise the epithelial cells of the gut, hence providing a good in vivo model for gastroenteritis due to these bacteria [3], [4].
Therefore, molecular imaging and diagnosis of the disease can be effectively followed by personalized treatment using the same molecular imaging vectors, a process referred to as theranostics.
This may indicate that the control of the later phases of senescence uses the same molecular machinery in both tissues (Additional file 10).
We therefore used the same molecular clock for both species (i.e., the one proposed by Ma and Bennetzen 2004) to estimate the radiation date between both species.
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CEO of Professional Science Editing for Scientists @ prosciediting.com