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There seems to be little difference whether BH or the mixed model approach is used to estimate FDR for limma and Cyber-T on our data set, but since the BH FDR produce values that tend to increase stepwise whereas the mixed model have a more smooth increase (more obvious if Figure 3C is plotted in higher resolution, not shown) we chose to use the mixed model FDR in the following.
However, it is considered an advantage to use the Mixed Model approach as more information is provided for the statistical test.
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Table 3 summarizes the association between the different case-mix variables, the stages of endometriosis, and surgical outcomes, using the mixed model regression analysis (univariate and multivariate analysis).
Data were analyzed using the mixed model of SAS.
Data were analyzed using the mixed model procedures of SAS.
This study investigated the statistical power for identifying nucleotide variants associated with quantitative traits using the mixed model methodology.
Variance analysis was conducted using the mixed model.
Estimates of differences in expression were calculated using the mixed model.
The between schedule comparison and the RTS,S/AS01E versus rabies comparison were done using the mixed model procedure adjusted for multiple comparisons using the Bonferroni method to correct for type I error.
Association mapping using the mixed model on SNP genotypes in the diversity panel as a whole also showed the highest significance in the region containing the GS3 gene (P∼2×10−7) (Figure 5B).
We used the Mixed Model module of SPSS for multilevel models [ 45] to examine these models.
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