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How did the company use the human genome sequence in its research?
Biotech companies use the human genome database to create DNA chips that measure levels of human gene expression.
Phoenix is the leading contender to become the home of the International Genomics Center, a collaborative effort by industry and universities to use the human genome to find cures for specific cancers.
This catalog "will change the way people think about and actually use the human genome, says John A. Stamatoyannopoulos, an ENCODE researcher at the University of Washington, Seattle.
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The Genomicus database v72.01 was queried using the human genome to investigate the genomic organisation of NASP family proteins [ 107].
The UCSC Genome Browser [ 29] served as the main source of genomic sequence, using the human genome assembly hg17.
To overcome this, a comparative genomics approach using the human genome was used to identify sets of orthologous tRNA genes that are probably functional.
The first great-ape genome projects used the human genome as a scaffold to help assemble genomic regions in which corresponding stretches of DNA lay in the same order and were present in a similar number of copies.
All genomic analyses were performed using the human genome version hg19/NCBI37 with annotations taken from Ensembl (version 60; Flicek et al., 2011 ).
All available 3'-UTR sequences (23,611) for human genes were extracted using the human genome version hg18 (NCBI build 36.1) from the USCS Genome Browser [ 58] and genomic coordinates for human genes from the Refseq database [ 59].
Eric Lander '78 – Leader of the Human Genome Project; founder/director of the Broad Institute, a partnership between Harvard, MIT, the Whitehead Institute, and other hospital systems with the goal of using the human genome to understand and treat diseases.
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