Now, we use the established multi-step ahead model to predict the population growth from the 36t h to 60t h month in Renren, from the 41s t to 51s t month in Twitter, and from 14t h to 20t h month in Gowalla.
The optimal search for machining parameters for the objective of minimum kerf together with maximum MRR is performed by using the established mathematical models.
In the present study we used this established model of OA to study the changes in expression of key structural molecules (aggrecan and type II collagen), the collagen-associated SLRPs (biglycan, decorin, lumican and fibromodulin), TGF-β1 and its associated downstream signaling molecule connective tissue growth factor (CTGF), and markers of altered chondrocyte phenotype – types I and III collagen.
Therefore, we could not use these established models as they are not able to represent the coupling between three different states of the VSD and the pore.
Rumbarger, et al. [31], used the established fluid traction torque model to calculate the friction power loss of the bearing roller, cage, and inner and outer ring raceway respectively.
Water and tillage erosions were estimated using the established water and tillage erosion models and total soil erosion was estimated using the 137Cs technique.
To assess the potential of using DARPins for topical anti-angiogenic treatment we used the well-established model of suture-induced corneal angiogenesis [ 36, 37].
To evaluate the effect of HQT, we used the well-established model of TNBS-induced colitis in rats which has resemblance to CD [ 21].
To mimic chronic preexisting cardiovascular disease, we used the well-established model of ApoE-deficient (ApoE−/−) mice fed an atherogenic diet for 16 weeks [ 8].
The aim of this study, therefore, was to use an established model of active cartilage resorption to compare the temporal expression of metalloproteinases and their inhibitors and correlate this with pro-collagenase activation and aggrecan and collagen release.
