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The possibility of linking SFE to the parachor and the additive effects of the polar and dispersive components of SFE as provided in the Owens and Wendt theory [ 13], all that made us use the additive model as a tool to describe the effects of polyurethane chemical structures on the SFE values of the polymer films.
The default in FBAT was to use the additive model as several studies have shown that the additive model performs well even when the true genetic model is not additive 34.
DOI: http://dx.doi.org/10.7554/eLife.00776.021 We next proceeded to use the additive model to directly compare the role of cytoplasmic genome variation to that of individual nuclear loci in controlling metabolome variation.
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In addition to three markers detected using the additive model, six markers were deemed associated with an imprinting effect when the phenomenon was accounted for; the directions of the imprinting effects of all six markers were consistent with previously reported studies.
When using the additive model, it is removed by minus, that is to say H t) − X t) is the series to be decomposed in the next step.
Figure 9 Additivity mismatch for Toulouse, defined as excess in total expected distortion (using the additive model) over the simulated overall distortion (true value), as a function of BER.
There was no significant SNP×SNP interaction effect examined as either a two-way or three-way interaction using the additive model.
These maps differed slightly from the relative risk map produced using the additive model as the relative risk in the additive model was more closely restricted to the areas of high population density.
There was no evidence of a cumulative effect of carrying risk alleles in multiple SNPs, nor was there any evidence of a two- or three-way interaction effect of the SNPs using the additive model (data not shown).
Among the SNPs with the minimum p value for each gene region, the associations as evaluated using the additive model were consistent across all three independent NHL studies (Figure 1) and were statistically significant for one or more of the most common subtypes (Figure 2).
However, we can say that the relationship between adult intelligence and DNMT3L genotype remained significant, by both the additive and dominant models, following sequential exclusion of the highest MHT scores over a large span of the data; from the maximum possible score of 76 down to a score of 67 using the additive model and down to a score of 59 using the dominant model.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com