Sentence examples for use protracted from inspiring English sources

Because the add-back low-dose hormone replacement should permit long-term use, protracted reductions in hormone exposure is possible.

We, however, consider the qualitative connotation of the term to be less arbitrary and use "protracted" as a relative term, indicating an evolutionary process with phases of stasis or even reversal.

The current study's temozolomide schedules used protracted and cumulative exposure to deplete AGAT, and the PBMCs were sampled at later time points to examine these cumulative effects.

Preclinical data from rhabdomyosarcoma and neuroblastoma xenograft models have demonstrated schedule-dependent activity for irinotecan, with superior activity seen when using protracted low-dose administration (Houghton et al, 1995).

Hence, we have used a protracted low-dose schedule of irinotecan in the present study.

He was delighted with this new game, but as his palindronic skills improved he failed to notice at first that, like all sedatives this one had begun to weaken with protracted use.

However, as a matter of good clinical judgment, it is prudent to consider all analgesics potentially nephrotoxic and to counsel against excessive, protracted use [46, 81].

After the Operation Trial and Evaluation, it was found that the aircraft were not suitably protected and survivable for protracted use in combat zones.

The often protracted use of antibiotics in our patients may also have detrimental sequelae on the microbial balance in CRS which requires further substantiation.

This possibility may be rectified by use of a protracted linker segment in the scaffoldin that would further distance the functional modules (CBM, cohesins) from the bacterial cell surface.

Although the toxicity profile of the existing TKIs may be reasonable in the setting of metastatic disease, it is unclear whether protracted use of these agents would be tolerated by otherwise healthy women.