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Further strengths of this study include the use of validated questionnaires and a validated survey methodology [ 11], and the high response rate, which minimized the potential for responder bias.
Another strength is the use of validated questionnaires that were published prior to the study.
However, our analysis was based on use of validated questionnaires along with evidence on high concordance between self-report instruments and clinical diagnosis of psychiatric disorders [13].
Strengths of the study are the large clinic-based sample from eight headache centres with high participation rates, and the use of validated questionnaires for establishing headache diagnoses and for assessing depression and anxiety.
The use of validated questionnaires is appropriate for measuring PROs in clinical trials [ 11, 12].
We minimized these biases by careful design, the use of validated questionnaires administered by trained interviewers, and robust analytical methods.
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The use of validated questionnaire and triangulating both quantitative and qualitative methods of data collection were the strengths of this study.
Strengths of the current study include the long-term nature, prospective design, frequent follow-up during study periods, robust analyses and use of validated questionnaire instruments.
The study benefits from long-term follow-up, prospective design, frequent follow-up during study periods, robust analyses and use of validated questionnaire instruments.
All other studies used subscales of (validated) questionnaires, self-developed and not yet validated questionnaires or single questions.
Further research should involve longitudinal studies with randomized sampling, the analysis of knowledge of workers about the CE and its applicability and use, by means of validated questionnaires and to observe the consistency of behaviour in relation to the CE.
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