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These studies require the use of validated endpoints to measure specific symptom relief as well as accompanying quality of life.
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It has increased the credibility and use of validated self-report measurement techniques as a quantifiable set of hard data endpoints and has contributed to a new appreciation of outcome assessment.
Strengths of the study are the large and unselected population and the use of validated diagnoses.
Another strength is the use of validated questionnaires that were published prior to the study.
Despite regular use of validated VAP bundles in our ICU, this remains relatively high.
The use of validated tools in our study further strengthens the reliability of our results.
Whenever possible the use of validated in vitro toxicology testing methods will be promoted.
Other strengths included the use of validated, patient reported outcome tools, which were assessed by researchers who were blinded to the type of hip arthroplasty, and the very high levels of complete follow-up data at the primary endpoint (95%).
We also recommend the use of validated satisfaction questionnaires.
The use of validated outcome measures should be encouraged.
Although widely accepted and used as validated endpoint in clinical trials evaluating public health interventions in Africa, its significance as causal factor for disease has been discussed controversially [22].
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