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However the sequencing and data processing burden is still the bottleneck for widespread use of unbiased sequencing.
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To elucidate the genetic basis and architecture of SUDEP, we used an unbiased sequencing approach based on whole-exome sequencing data.
Such abundant read sequencing enabled us to obtain almost full-coverage contig sequences for the viral segments using de novo assembly, suggesting the importance of this result in terms of being able to evaluate uncharacterized emerging infectious agents using an unbiased sequencing technique at the outbreak of a pandemic.
We therefore sought to obtain the complete sequences of the S, M, and L segments using an unbiased sequencing approach, then phylogenetic analyses to determine the relationship of the IQT9646 isolate to other viruses within the Orthobunyavirus genus.
We then examined the correlation for individual PWMs using an unbiased sequence set.
The use of k-mer frequencies is premised on the availability of an unbiased sequence set reflecting the overall repeat character of the genome in question.
Here, we explored human small RNAs by unbiased sequencing of RNAs with sizes of 19 40 nt.
The use of next-generation sequencing to study the entire small non-coding RNAome in CSF from AD patients and controls would be another option that may allow for a complete unbiased and quantitative measurement of CSF miRs.
Also, the use of an unbiased stereology technique should be considered.
Data for proliferation were obtained by using methods of unbiased stereology.
Calculation of unbiased autocorrelation sequence of noisy speech signal.
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