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The use of transgenic mouse models allows us to dissect the role of AMPK and other signaling pathways in the intact perfused heart and in vivo.
The recapitulation of the mechanisms underlying the onset of AD is most commonly achieved through the use of transgenic mouse models of the disease state6,7.
This trend, together with the decoding of the human genome and the resulting design and use of transgenic mouse models of human diseases, demands that innovative imaging approaches are developed for man and mice.
Identification of the intestinal stem cell marker Lgr5, isolation and in vitro culture of Lgr5+ intestinal stem cells and the use of transgenic mouse models have significantly facilitated the studies of intestinal stem cell homeostasis and differentiation, therefore greatly expanding our knowledge of the regulatory mechanisms underlying the intestinal stem cell fate determination.
In our view, the use of transgenic mouse lines is preferable for such investigations.
The use of transgenic mouse line with fluorescent protein-labeled is another sophisticated methodology [ 35].
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Transgenic fish are an interesting and valuable alternative to the use of transgenic mice as models for genome manipulation.
Here we describe a strategy that combines the use of transgenic mice with live microscopy to allow in vivo imaging of hematopoietic cell behavior in real time.
From this overview it is concluded that, compared to the number of studies about drug self-administration, the use of transgenic mice in addiction-related models has been rather scarce and should be further encouraged.
This parallels a rise in the use of transgenic mice internationally, PETA says.
The use of transgenic mice in which subtypes of neurons are labeled with a fluorescent protein has greatly facilitated modern neuroscience research.
More suggestions(15)
use of transgenic alfalfa
use of transgenic soybean
use of different mouse
use of several mouse
use of transgenic technology
use of monoclonal mouse
use of transgenic intervention
use of transgenic animal
use of immunocompromised mouse
use of transgenic yeast
use of irradiated mouse
use of alternative mouse
use of transgenic overexpression
use of transgenic zebrafish
use of mutant mouse
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