Sentence examples for use of trail from inspiring English sources

Therefore, for the clinical use of TRAIL in cancer therapy, it is extremely important to overcome TRAIL resistance.

Assessment of TRAIL-receptor expression patterns may have therapeutic implications for the use of TRAIL receptor agonists in HCC therapy.

The data presented in this study indicate that use of SMAC mimetics is a suitable strategy to antagonize therapy resistance caused by all these central defects in the intrinsic apoptosis machinery and delineates the combined use of TRAIL together with SMAC mimetics as a useful strategy.

A significant problem for clinical use of TRAIL is effective delivery and sufficient bioavailability in tumor lesions of the recombinant protein or agonistic TRAIL-R antibodies.

Despite the fact that TRAIL can potently induce tumor cell apoptosis, TRAIL resistance observed in some cancer cells critically challenges the use of TRAIL as a gene therapy agent.

"The Squibb Park Bridge design makes use of trail bridge technology," the signs explain.

The use of trailing edge flaps on top of individual pitch control increases the reduction in the levelised cost of energy to 1.27%.

The Angeles Crest 100 makes use of trails that crisscross the national forest.

Furthermore, given the importance of TRAIL-R2, we hypothesized that the use of TRAIL-R-specific variants that specifically induce apoptosis via TRAIL-R2 might increase the efficacy of the MSC.sTRAIL system further.

In contrast, some pathways include mediating conditions where urban greening either changes an exposure (such as air pollution) or behaviors (such as active use of trails) that lead to beneficial health outcomes.

No admission charge; car park charge (from £3.40 a day) covers use of play trail, play areas, and tree-top trail.