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The topological analysis performed by EEEP may also be complemented by the use of surrogate methods which consider the deviation of residue composition within a gene from that of the 'background' genome sequence [ 45- 47].
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The need for continuously measuring bedload intensity and dynamics has therefore increased the use and enhancement of surrogate methods.
To account for trivial locking that may be induced by the nonstationarity of the firing rate during this interval, we derived the significance of the PLV by use of a surrogate method (Random Shuffling Surrogate in Materials and Methods section).
This issue can be addressed through the use of surrogate-based methods for feasibility analysis.
Rapid evaluation of anti-TB drugs will require novel methods including the use of surrogate end-points.
These questions were recently addressed using surrogate methods, those that do not require inference of phylogenetic trees, such as the analysis of BLAST scores.
Another disadvantage of the viscosimetric method is that the use of native unmodified substrate is highly preferred compared to the use of surrogate substrates that are chemically modified [23, 26].
The first is continued use of surrogate endpoints — or at least, initially, more research to find out if wider use of surrogate endpoints for additional cancers is valid.
Advantages of this method include not only making fewer modeling assumptions, but also establishing procedure that adapts to missing values through the use of surrogate measures [ 4].
The third conclusion concerns the widespread use of surrogate variables.
The use of surrogate intrinsic subtypes gave inconclusive results.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com