Sentence examples for use of surrogate end from inspiring English sources

The use of surrogate end points of quality of life can be useful within a project of quality of life assessment.

Furthermore, the use of surrogate end points in SCLC has not been explored.

The use of surrogate end points provides a powerful tool to accelerate and make decisions more efficient.

A further dimension in which the use of surrogate end points of quality of life could be misleading is palliative care.

Moreover, the use of surrogate end points as outcomes of effectiveness has been extended to survival and even to the assessment of quality of life.

Obstacles to adaptive designs may be the duration of treatment, as well as the time to treatment effects and use of surrogate end points.

Rapid evaluation of anti-TB drugs will require novel methods including the use of surrogate end-points.

Dr Carol Fabian [ 3] discussed use of surrogate end-point biomarkers to assess prognosis and the risk for developing breast cancer in patients.

All these obstacles have favoured the use (and the abuse) of surrogate end points of quality of life, the role of which has invaded the main dimensions of quality of life research, jeopardizing the correct assessment of health-related quality of life as a patient-outcome.

As a consequence, clinical data extracted from current clinical practice can be used: (i) to provide information of the appropriateness of patient management in the real world, through the use of indicators consisting of surrogate end points (e.g. response rate etc).

The use in clinical research or clinical practice of surrogate end points such as clinical benefit or pain control is not a problem by itself.