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More importantly the pro-death effect of PES was found to be more specific for the lymphoma cells compared with normal PBL, strongly encouraging the use of such molecule in vivo.
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The use of such molecules rather than synthetic polymers is a promising avenue for generating biodegradable green materials and ensuring the biosafety of medical materials such as dental and bone implants.
Comparison with calculated electronic structure shows that the construction of chromophores that consist of electron donating and accepting units does not always follow the simple rules that are generally used in the design of such molecules.
Reports showing that endogenous molecules act through TLR4 have been questioned as studies using low-endotoxin preparations of such molecules failed to confirm these data (reviewed in [ 9]).
A grid of such molecules can be used for computer memory.
But, overcoming multidrug resistance, by the use of such small molecules still remain unexplored.
The capacity to genetically modify αB-crystallin for improved ability to block amyloid fibril formation provides a platform for the future use of such engineered molecules in treatment of diseases caused by amyloid fibril formation.
A significant limitation to the use of such 'foreign' molecules was their immunogenicity.
The ultimate goal of using such molecules is the modulation of protein function through controlled interference with the underlying binding events.
In this review, we will highlight signalling pathways involved in human diseases that could be targetable by AhR modulators and discuss the feasibility of using such molecules in therapy.
These results demonstrate the utility of this new computer simulation model in predicting xenobiotic behavior in plants and the potential use of such models in rational design of herbicide molecules for optimal plant uptake and whole plant allocation.
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