Then, we focused in the important issue of the use of statistical methodology adopted in this area, and claimed that more widespread use of statistical techniques is needed.
Meta-analysis of high-throughput expression data using a collection of statistical methodologies leads to the identification of robust tumor gene expression signatures.
We have previously described an automated real-time safety monitoring tool, Data Extraction and Longitudinal Trend Analysis (DELTA), that is able to perform larger numbers of concurrent prospective analyses using a variety of statistical methodologies and alerting thresholds [ 18].
This required modification and development of statistical methodologies.
Transparent reporting of results with clear elaboration of statistical methodology used to risk-adjust data and identify outliers and peer-review of outcomes in an environment seeking to improve quality of care rather than to ostracize individuals or units is essential [ 14].
Since there are concerns about safety, multiple interim comparisons over time between treatment groups are called for which, in conjunction with the use of multiple outcomes, require an extension of statistical methodology to meet this requirement.
Michael made important contributions to many areas of statistical methodology including experimental design, clinical trials and computational statistics.
Statistical distributions are the foundations of statistical methodology in both theory and applications.
Development and implementation of statistical methodology: CAT, RLF, NFO, LDA.
Mathematical description of transcription regulation by use of statistical mechanics methodology [ 19- 21] as well as experimental data [ 25, 35, 36] also suggest that the Hill function is very well suited for describing a whole range of mechanistic processes causing nonlinear transcription responses.
