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Their approach relied on an estimated error rate from the sequencer without the use of sequencing controls and included sequencing each sample twice to correct for sequencing error, which would present practical problems for sequencing larger numbers of samples collected from an outbreak.
Biological nitrogen removal by the use of Sequencing Batch Reactors (SBRs) is today an accepted and well proven model.
Nowadays, the use of sequencing allows for the collection of enormous amounts of data with the ability to decipher the meaning of the data and attempt to translate these into the treatment of cancer patients.
Even trained geneticists are not entirely comfortable with the use of sequencing in daily practice.
HIV-1's high mutational capacity has allowed the use of sequencing and phylogenetic analysis, particularly of the envelope gene [2], [3], to objectively identify HIV-1 source partners and to investigate patterns of HIV-1 transmission.
One possible solution is the use of sequencing technologies that produce longer sequence reads.
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In addition, the use of sequences from the HVR1 region of mtDNA has permitted us to consider nucleotide variations.
Clearly the use of sequence homology to screen the genome for known sequences is useful.
Abstraction played a large part in his attempt to make images that "passed" but that also communicated, as did his use of sequences.
Analysis of these comprehensive specificity profiles is facilitated through the use of sequence-specificity landscapes (SSLs).
This method relies on the use of sequence-specific endonucleases such as homing endonucleases.
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