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Furthermore, modeling binding sites this way facilitates the use of sequence representations that are position dependent, yielding a more detailed model of the binding site.
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10.7554/eLife.00801.009 Figure 4. Temporal aspects of sequence representations.
In this study, two kinds of sequence representation approach are used to transform the protein sequences into feature vectors, including amino acid composition and a novel local descriptor.
Aligned sequences were used to generate peptide sequence representations as logos using web logo (http://weblogo.berkeley.edu) [45].
The use of reduced representation libraries followed by sequencing [Genotyping by Sequencing (GBS)] is one such approach [ 9].
The use of reduced representation libraries (RRLs) was first proposed in humans to efficiently find SNPs using Sanger sequencing [ 11].
This poor sequence representation has an impact on the current use of such databases for sequence identification.
Half of the DAs (50%%) provided information about an update policy, and eight (40 %) (not mutually exclusive) showed the negative and positive features of options in equal detail (using similar fonts, sequence, and representation of statistical information).> -wrap-foot> aminumum-maximum scorangesnges from 0 to 16 None of the 20 identified DAs met all minimum standards.
A variety of strategies can be used to collapse redundant input sequences into contiguous consensus sequences, including the simple collapse of identical sequences, the use of de Bruijn graph representation (Zerbino and Birney 2008) to generate a consensus view of overlapping sequences, and more time-consuming binary alignment-then-collapse methods.
Such geographic sequence representation could bias our analysis toward a representation of the history of HEV mainly in China and Japan.
For each read, positions of the strongest BLASTN hit on the BAC were used for graphical representation of sequence coverage.
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