Sentence examples for use of sequence features from inspiring English sources
The novelty of our method lies in the use of sequence features representing biological knowledge for input encoding.
Jiang et al. (2007) developed a method consisting of 20 modules, each of which was optimized using a subset of sequence features specific to a particular starting residue.
We are expanding on this analysis by creating a model that evaluates the interaction of these genomic vectors using the same set of sequence features.
The program can be used for sequence editing, annotation of sequence features, handling of output from high throughput sequencers, or from BLAST searches, as well as for various population genetic analyses.
Considering the fact that a large number of false positives/negatives would occur in our constructed datasets, due to conspicuous incompleteness of experimental information, we realized that as predictions were done on the basis of sequence features, use of a single binary classifier might compromise the sensitivity of our prediction.
We used the aforementioned three sets of sequence features, and trained three SVM classification models.
As demonstrated in the case studies outlined here, experimentalists targeting potential functional regions for a gene could use a quick display of a variety of sequence features to form a basis for such predictions.
Structural analysis of sequence features was performed using routines that have been implemented within the CHAIN program [ 32] and that were used to generate RasMol [ 33] scripts for each category of co-conserved residues identified by the mcBPPS program.
Sequences are analysed using a range of analysis tools for prediction of sequence features.
On the Youn et al. (2007) dataset, INTREPID is more accurate than the variant of their method that makes use of only sequence features.
In the present study, we have developed a highly robust new method to predict sumoylation sites with the use of various sequence features and flexibility/disorder information.
