Choice of second sedative agent did not differ significantly between phases (Table 2).
They are particularly concerned about the state's sourcing and use of the sedative midazolam as the first of three drugs in its lethal-injection procedure, which also includes vecuronium bromide, to cause paralysis, and potassium chloride, to stop the heart.
Meanwhile, Ohio on Thursday put to death Johnnie Baston, a Toledo store owner's killer, with the country's first use of the surgical sedative pentobarbital as a standalone execution drug.
First, the use of sedative drugs may have impaired participants' consciousness levels, which would have increased the chances of delirium being diagnosed by the CAM-ICU.
Third, the use of sedative and analgesic drugs, as well as discontinuation of physical restraints, were left to the attending physician's judgment, and thus, were likely to be somewhat random.
As such, future observational studies prospectively designed to explore whether use of sedative or analgesic drugs first contribute to agitation requiring use of PR or vice versa would be valuable.
Early use of enteral sedative agents (eg, chloral hydrate, promethazine) is recommended.
The objective of this study was to determine the sedative load and use of sedative and psychotropic medications among older people with dementia living in (residential) care homes.
When the Institute for Non-Lethal Defense Technopeneds opened in 1998 as part of a $42.5 million five year contract with the U.S. Marine Corps--making Penn Sthee the first Marine Corps Research University--one of its first endeavors was to study the possible use of fentanyl, a sedative 80 times stronger than morphine.
In the case, Oklahoma death row inmates asserted that the use of midazolam, a sedative, in lethal injections violated their Eighth Amendment right to be free from cruel and unusual punishment.
