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There are also concerns about the use of rodent models and the reliability of the treatment outcomes.
The importance of kinetic force plate studies of locomotion in small animals has grown recently with the increasing use of rodent models for studies of musculoskeletal diseases.
Traditionally, the use of rodent models in assessing the carcinogenic potential of chemicals has been expensive and lengthy, and the relevance of the carcinogenic effect to humans is often not fully understood.
Finally, while the use of rodent models for reproductive investigation is generally well accepted, a number of differences must be recognized.
The results demonstrate a significant difference in ACC expression between human and rodents, which may introduce difficulties for the use of rodent models for development of ACC inhibitors.
The use of rodent models (e.g., mice and hamsters) will be explored.
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The use of rodent model to understand immunosenescence may help the development of treatments to improve the immune fitness of the aged.
Tests used on rodent models of impulsivity share strong parallels with tasks used to assess this trait in humans, and studies in both suggest a crucial role of monoaminergic corticostriatal systems in the expression of this behavioural trait.
Indeed, several seminal discoveries and human therapies have been made using the premise of rodent models.
The expanded use of various types of rodent models has produced some advances in the study of ED, and neurophysiological studies using various animal models have provided important insights into human sexual dysfunction.
Hence, using a judicious choice of rodent models allows researchers to investigate different subtypes of breast cancer by creating specific opportunities as a platform to study underlying biological mechanisms of mammary carcinogenesis, which cannot be directly investigated in humans.
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