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The particular genes revealed here were, moreover, supported by a combination of validation by qPCR, biological meaning and the use of robust statistical analyses with stringent adjustments.
Data were analysed by use of robust statistical multi-way procedures.
Strengths of our analysis include the use of robust statistical analysis that takes into account the complex interplay between variables.
Large patient heterogeneity makes generalized pre-ECMO mortality prediction a persisting challenge, despite use of robust statistical methods.
As such, assessment of mortality surveillance patterns requires the use of robust statistical analysis methods that will optimise findings leading to appropriate policy decisions from evidence-based research.
The strengths of this analysis include the use of IPD, an analysis of whether text messages are more effective in patients with certain characteristics, the use of robust statistical techniques to account for within-study and between-study differences, and our focus on Africa where our research is most needed.
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This study has a number of strengths, including a very large sample size, prospectively collected data, and the use a variety of robust statistical techniques to address potential biases, all of which reached the same conclusions.
By using a number of robust statistical tests to detect intra-host recombination, we identified the presence of recombinant sequences in different tissues and correlated the extent of recombination with precise details relating to autopsy and tissue pathology reports.
These data were analyzed by using a set of robust statistical methods.
Finally, the use of a robust statistical analysis with TSA precluded us from making overly optimistic conclusions [ 37].
Specifically, the small sample size, along with other study design features, prohibited the use of more robust statistical methods for comparing the cross-sectional and prospective incidence rates, such as equivalence tests[33], and may have also led to reduced precision around the assay FRR estimates[9].
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