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However, the use of rat models in mechanistic studies has been limited due to lack of genetically modified rat strains.
The lipid-lowering activity of AM preparations has been documented with the use of rat models with artificially induced hypercholesterolemia [ 14].
The picture emerging from reviewing this literature is very encouraging, in terms of the potential use of rat models in the study of higher-level visual functions.
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Alternatively, the use of knockout rat models would greatly improve our comparison and mitigate inter-strain uncertainties.
The aim of this study was to determine, with the use of a rat model, the expression of tumor necrosis factor (TNF -α, iTNF -αeptors, and TNF-α–convertits enzyme in pereceptorsrand lesions of early premaTNF-α converting
Moreover, in view of the therapeutic use of TGFβ1 for nucleus pulposus regeneration, the limitation in the use of the rat model needs to be carefully considered.
However, use of this rat model for mechanistic and chemopreventive studies is limited due to lack of genetically modified rat strains.
The objective of this study was to investigate the relationship between endometriosis and bone mineral density with the use of a rat model.
First is the use of a rat model to study adrenocortical recovery after hypnotic infusion.
The scope of sbv IMPROVER Species Translation challenges was to assess the limits of using rat models to predict human biology in the specific context of bronchial epithelial cells exposed to various stimuli.
First, we have assessed JAM-A expression at the protein and mRNA level in a range of commonly used rat models of hypertension.
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CEO of Professional Science Editing for Scientists @ prosciediting.com