Sentence examples for use of predictive markers from inspiring English sources

Prescription of chemotherapy with no benefit to the patient could be limited through identification and use of predictive markers.

The inconsistent findings of most studies, which may be explained by insufficient statistical power, differences in the experimental setup and patient cohorts have prevented the widespread use of predictive markers in patients with primary and metastatic CRC.

It is ultimately by better defining 'sensitive' patient populations, through the use of predictive markers, that we will make best use of our available and up and coming cytotoxic and target-specific therapies.

Many studies have identified predictive markers or cassettes of predictive markers using gene expression measurements [ 3, 17- 21].

With this background of inconsistent data for clinical utility of p53 status and absence of predictive markers for taxane use, we undertook a retrospective, exploratory analysis in BIG 02-98 to investigate the prevalence, and prognostic and predictive value of different types of TP53 mutations.

Taxanes are widely used in gastric cancer, and the identification of predictive markers for specific drugs would be of value in tailoring therapy to the specific profile of individual patients and tumors.

Conclusions: The reduced plasma levels of IL-6, IL-8 and IL-11 in women with spontaneous abortion may be related to the underlying aetiopathogenetic mechanisms, however, there is no sufficient evidence for their use as predictive markers of pregnancy outcome.

Exploration of specific molecular changes that can potentially be used as predictive markers of response to regorafinib.

Therefore, MCM2 and MCM3 may be used as predictive markers of more aggressive tumor behavior and potentially as important markers to predict the risk of malignant transformation.

PD-1 rs2227982 C>T, rs2227982:C>T and rs10204525 A>G SNPs might be used as predictive markers of the susceptibility to ESCC for the Han nationality in a high-incidence population from Northern China.

These results suggest that JAK expression levels can be used as predictive markers of enzastaurin sensitivity.