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Although many previous studies have compared one of the available treatments with another, none of them have provided sufficient evidence for the superiority of a particular treatment protocol, which may be the result of the use of poor study and assessment techniques.
Early detection research has been severely hindered by the use of poor study methodology.
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Further studies show that use of poor quality health services can be a negative and disempowering experience for rape survivors [ 9, 10].
A growing number of meta-analyses vary in their conclusions on the effectiveness of probiotics against IBS, in part because of inadequate sample size, poor study design and use of various probiotic strains in the reviewed studies.
One of the triggers for inducing cyst development is the growth on energy poor carbon sources such as the use of nutrient poor CENBA in this study [ 16, 34].
The current evidence is limited by poor study design, inadequate use of standardized questionnaires, and heterogeneous populations studied for variable lengths of time.
Reasons for these shortcomings include low patient recruitment, poor study design, and ineffective use of animal models [ 1, 2].
Methodologically poor study designs are often used to evaluate CPWs and this compromises the quality of the existing evidence base.
One study [ 51] even divided the more generally used class of "poor" outcome into deteriorated (< 30) and minimal improvement (30 50).
And the Europeans and Americans are making poor use of those people: another study shows that staff who do a spell abroad take longer to move up the organisation than people who stay at headquarters.
This failure to increase the degree of methodological rigor in published research is of concern because significant resources are used conducting studies of poor methodological quality and such research may produce scientifically invalid conclusions that influence future research and policy.
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