Sentence examples for use of pluripotent stem from inspiring English sources

A second alternative involves the use of pluripotent stem cells, which can give rise to all the body's cell lineages.

Here, we describe how the use of pluripotent stem cells (PSCs) may help in addressing the physiological and pathological relevance of mitochondria for the human nervous system.

Says Wells, "The therapeutic use of pluripotent stem cells is no longer science fiction.

This review will summarize current advances in lung stem cell research and discuss technical challenges for possible therapeutic use of pluripotent stem cells in lung tissue regeneration in the future.

Our study not only established an ideal platform to investigate the transcriptional network regulating the RPE cell fate determination, but also provided an alternative strategy to generate functional RPE cells that complement the use of pluripotent stem cells for disease modeling, drug screening, and cell therapy of retinal degeneration.

Furthermore, our data show that the mechanism by which Pten null ECCs emerge in vitro and cause tumors in vivo is through increased survival and self-renewal, due to failed repression of the transcription factor Nanog. Risk of tumor formation constitutes one of the major barriers to the use of pluripotent stem cell (PSC) lines in regenerative medicine.

In this regard, generation of cellular disease models using the induction of pluripotent stem (iPS) cells from patient skin fibroblast has opened new horizons [ 42, 43].

As an example, we imported 19 gene symbols (listed in gene example 1 in the homepage) that were used for induction of pluripotent stem cells (34) and selected 13 developmental stages during mouse sperm development (stage example 1 in the homepage).

The SNP arrays have been used in several studies of pluripotent stem cells and they have been mostly utilized for the copy number analysis [ 8, 21- 23].

Now cardiologist and stem cell researcher Joseph C. Wu, MD, PhD, and postdoctoral scholars Hongchao Guo, PhD, and Lei Tian, PhD, have found a way to use human embryoid bodies — balls of pluripotent stem cells that mimic aspects of the early human embryo — to examine at the single-cell level how nicotine affects cell development.

Therefore, our study represents a first step toward the development of a method of differentiation in which simple manipulation of the cell cycle using small molecules could direct differentiation of pluripotent stem cells toward specific cell types without the need of exogenous growth factors.