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Finally, the use of other statistical techniques that can model moderators and mediators of the intervention effects on outcomes (e.g., structural equation modeling) may be useful.
Replicate datasets will enable the use of other statistical tests, which will likely detect a larger subset as significantly different, and may thus help to identify additional regulatory elements that are not covered in our examples.
Although authors have suggested the use of other statistical approaches to compare screening modalities [ 10, 11], the area under the full ROC curve remains the most commonly used test for paired screening trials in major American journals [ 1- 3].
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There are also dozens of other statistical software products used for HSR purposes.
The presented approach should be validated by application of other statistical techniques and by use of German wide inventory data.
Achieve that little nugget and all sorts of other statistical gems will follow.
This method was designed to be modular; therefore, researchers can explore the use of other bioinformatics and statistical tools that best fit their data.
Although the replication of our method by other researchers is extremely desirable, we were unable to develop a syntax of our procedures for use in other statistical packages.
The final model is established on the basis of additional statistical analysis using other statistical criteria (coefficient of variation, adequate precision, Mallow's Cp statistic), the convenient results obtained, ensuring a satisfactory quadratic regression model, including all main parameters and their quadratic terms.
Nonetheless, this link was demonstrated when using other statistical approaches, including contrasting of weight gains between responders and patients who did not respond, by identifying the degree of improvement associated with every 1-kg gained at 6 weeks, and by calculating the conditional probability of therapeutic response given various amounts of weight gain.
A careful use of design of experiments and other statistical methods allow to clean data from systematic effects and outliers.
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