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Exact(1)
With the Bayesian approach inference in random-effects models is exact, whereas in frequentist analyses (e.g. with the R function lmer in the lme4 package) it is only approximate and understates the uncertainty in the estimates because of the use of only point estimates for the variance components [9].
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The interpretation of our findings is limited by moderately wide confidence intervals, the use of only single time points, and especially by our incomplete knowledge of how results in rats would relate to humans.
Several studies have now looked at the effects of BaP or its metabolites on mammalian gene expression [ 6- 10]; they have been limited, however, by the use of only one time-point or exposure concentration, have investigated only one cell type or have used DNA microarrays with a limited number of genes.
In addition, the use of only one data collection point obviates the need for matching students who participated in the first data collection to students who participated in the second one.
The statement being: the impact of the pursuit of justice and equality sometimes requires the use of only one person's breaking point to facilitate large-scale change.
The functional approach to sampling density function synthesis using transient and measurement density functions can be understood as improvement of the sampling density design of the auxiliary particle filter which uses only point estimate of the transient pdf.
However, we cannot at this point recommend the use of only 14 supervised TEE examinations for acquisition of ICU TEE competency when using a simulator, when the current recommendation is 35[13]].
In their preferred estimates, as well as in these alternatives, NIOSH/NCI used only point estimates of parameters and did not take into account their statistical variability.
However, using only point queries is insufficient.
The latter can be used to produce not only point estimates of fine-scale reconstructions or macroscopic observables, but more importantly, predictive posterior distributions on these quantities.
LeadCare is also the main instrument described in 2013 guidelines by a CDC advisory committee for point of care BLL testing [ 31] and the only point of use device described in the 2011 WHO brief guide to analytical methods for measuring lead in blood [ 32].
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Justyna Jupowicz-Kozak
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