Sentence examples for use of murine models from inspiring English sources

These findings support the use of murine models of Aβ deposition to develop novel strategies for the therapeutic management of patients afflicted with AD.

The modeling of human disease in vivo through the use of murine models represents a powerful, indispensable tool for investigating the immune and genetic mechanisms contributing to a clinical disease phenotype.

However, the use of murine models is restricted by costs, the requirement of specialized facilities and personnel, legal requirements and ethical considerations.

The use of murine models and tissues in this study was carried out in strict accordance with the recommendations in the Guide for the Care and Use of Laboratory Animals of the National Institutes of Health.

The preclinical evaluation of new therapies relies on the use of murine models of the disease.

The use of murine models has proven to be fruitful to study the several stages of the disease.

This has been permitted by the use of engineered murine models of human breast cancers where β1-integrin expression has been specifically disrupted in the mammary luminal epithelium.

The use of knockout murine models has provided compelling evidence for the essential role of Dicer in mature miRNA production.

We further demonstrate in vivo, by the use of a murine model of glaucoma filtration surgery, that SPARC deficiency can maintain the surgically-induced wound for a longer period of time compared to WT.

The study most relevant to RA in the Cramer et al. publication involved the use of a murine model of arthritis [ 1].

The use of a murine model for the characterization of B. abortus IVI proteins as potential protective antigens is likely not the optimal animal model for simulation of the disease state in the natural host species.