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Use of multiple medication use is not the same as having comorbidities, in this sample.
The use of multiple medication is a rational therapy for many patients, but it is also a well-known risk factor for patients' health as multiple medication is associated with adverse drug reactions, interactions and non-adherence to drug therapy [ 26], and the rate of non-adherence increases with an increasing number of drugs [ 27- 35].
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Due to multiple medical conditions and polypharmacy (defined as the use of multiple medications and/or administration of more medications than are clinically indicated [ 5]), in addition to age-related changes in pharmacokinetics and pharmacodynamics, care home residents are at high risk of adverse drug events (ADEs) [ 6- 8].
The children's medical complexity derives from the use of multiple medications, dependence on respiratory equipment requiring frequent adjustment, and heavy reliance on home care-givers with substantial clinical expertise to maintain health [ 2].
2 Additional situations also include over-use of medications at a higher frequency or for longer durations than clinically indicated, under-use of medically indicated medications based on ageist or irrational reasons, and use of multiple medications that have documented drug drug interactions or drug disease interactions.
Regular use of multiple medications that have this effect has been linked to cognitive impairment and memory loss.
The simultaneous use of multiple medications, a phenomenon known as polypharmacy, is a growing problem among seniors.
In November, the Army issued a new policy on the use of multiple medications that calls for increased training for clinicians, 30-day limits on new prescriptions and comprehensive reviews of cases where patients are receiving four or more drugs.
Still, given the depth of the medical problems facing combat veterans, as well as the medical system's heavy reliance on drugs, few experts expect the widespread use of multiple medications to decline significantly anytime soon.
The factors associated most strongly with ADR were advanced age and use of multiple medications.
Background: Polypharmacy (ie, the use of multiple medications and/or the administration of more medications than are clinically indicated, representing unnecessary drug use) is common among the elderly.
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