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The TR technique requires the use of multiple Line Arrays (LAs) in a Time-Reversal Mirror (TRM) to accurately predict the source location and its characteristics.
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But the team's use of multiple lines of evidence makes the case intriguing, he says.
Electroencephalography (EEG) recording and drug administration is commonly used for neurological experiments in rats, but is typically cumbersome due the use of multiple lines.
The strength of the manuscript is the use of multiple lines of evidence to justify the majority of the conclusions.
Use of multiple lines marginally improved prediction accuracy for B2 but did not affect or slightly decreased prediction accuracy for B1 and W1.
These were used as part of multiple lines of evidence in establishing the DNAPL source mass and architecture.
Indeed, assuming that different treatments are used in equal amounts in the host population, the use of multiple first line therapies would have two main benefits, i.e. the inability of the parasite to adapt to a variable environment and the reduced drug pressure as the rate at which a given treatment is used would be lower than if it was the only one available [33].
Despite logistical challenges, the simultaneous use of multiple first line therapies is supported by mathematical models, 66– 68 and concurrent availability of AL and ASAQ, as implemented in some countries in West Africa 4 may provide a practical means to test this strategy directly.
This effort is the most analogous to the current study due to the use of multiple founder lines.
Although the use of multiple founder lines introduces more alleles and decreases relative effect size, the process is much more analogous to human association mapping.
Importantly, the use of multiple cell lines harboring different oncogenes and representing varying degrees of transformation in different species suggests that the regulation of SOD3 gene expression is not cell line-specific.
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CEO of Professional Science Editing for Scientists @ prosciediting.com