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This may explain many farmers' use of multiple antibiotics.
There is, however, no evidence from this study that indicates that the use of multiple antibiotics is effective.
The use of multiple antibiotics and antibiotic cycling has been proposed as a way to prevent the evolution of antibiotic resistance [e.g. [ 55]].
The use of multiple antibiotics among these patient populations probably explains these findings, as Pseudomonas spp. tend to be more resistant to antibiotics than other Gram-negative bacteria.
The frequent use of multiple antibiotics in the most severely ill patients could lead to the acquisition of, or alternatively the transformation to, highly virulent strains of P. aeruginosa that pose a significant threat to the patient.
These tools accelerate mutant construction and discovery, but issues of transposon insertion polarity, growth inhibition due to use of multiple antibiotics, and unknown expression levels from promoters on plasmids limit complementation and interpretation of results (12, 13).
Similar(52)
Perhaps we should follow the lead of the Crohn's disease gastroenterologists 24 25 and proceed with a therapeutic clinical trial using a regimen of multiple antibiotics in patients with persistently symptomatic, advanced-stage sarcoidosis.
In any case, and despite initial reports of multiple antibiotic sensitivity, [ 11, 12], the spread of resistance [ 13] and the hypersensitivity of rabbits to many antibacterial agents precludes the aggressive use of antibiotics in this species [ 14].
For instance, the use of multiple pesticides or antibiotics with different modes of action can slow the evolution of resistance (Georghiou and Wirth 1997).
Other risk factors for serious fungal infection are the nature of the critical illness, use of immunosuppressive therapy, presence of neutropenia, use of multiple broad-spectrum antibiotics, use of total parenteral nutrition, and presence of an indwelling catheter [ 6].
However the rising number of immunocompromised people, unwarranted use of multiple broad spectrum antibiotics and the advent of implanted medical devices [ 5] has paved the way for rare non albicans Candida species [ 6] as agents of invasive mycoses and nosocomial bloodstream infections [ 7].
More suggestions(15)
use of multiple treatment
use of multiple forecasts
use of multiple jurisdictions
use of multiple impressions
use of multiple braces
use of multiple indices
use of multiple narrators
use of multiple paths
use of multiple acceptors
use of multiple measures
use of multiple settings
use of multiple media
use of multiple resonances
use of multiple microprocessors
use of prophylactic antibiotics
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