Sentence examples for use of lower dose from inspiring English sources

Because of the technical complexity associated with delivery of 24 Gy in a single session, there has been an ongoing search for tumor radiation sensitizers that would enable use of lower dose per fraction via currently affordable technologies, preserving the improved outcome provided by the higher exposures of single dose or hypofractionated schemes.

Strategies to decrease the risk for damage to the gastrointestinal tract have included the transition to other types of drugs, use of lower dose systemic NSAIDs, and the use of topical NSAIDs, but there are still patients who require more chronic exposure to higher dose therapy.

Because of increased toxicity with delivery of SBRT to large treatment targets or following re-treatment, there has been an ongoing search for tumor-selective radiation sensitizers that would enable the use of lower dose per fraction with increased efficacy (Senthi et al, 2012).

The cooperative roles of miRNAs are important for the treatment of DN because they might enable the use of lower doses of individual miRNAs and thus increase treatment selectivity43.

One reason is that the side effects stemming from the use of lower doses of some boosters are poorly understood.

Patients who had been taking one or two pills a day would see higher costs, and even if future evidence supported the use of lower doses of the drug, patients, insurers and government health plans would not save money.

Since propofol has some dose-dependent secondary effects, the use of lower doses, especially the ones designed for this age group, helps to avoid them.

New mechanisms of action have been described, supporting the use of lower doses, possibly with the same efficacy and less adverse effects.

The authors of a white paper by the Dutch non-profit organisation Access to Medicine say a lack of access to specific antibiotics can lead to less appropriate drugs being prescribed for an infection, or even the use of lower doses – both of which increase the risk of antibiotic resistance – as well as delay for treatment.

These results indicate that combining agents that act on different neuronal targets may be more powerful than either treatment alone, enabling use of lower doses of each compound, thereby attenuating the adverse effects of the individual drugs.

In the U.S., ezetimibe supplanted statins to some extent and led to use of lower doses of statins.