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It permits easy and investigator-independent use of laser stimulation in the MR scanner.
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The study was a double-blind, prospective, three-group parallel randomised controlled trial, using sham laser in the control group with other arms using 0.2 and 0.8 J of laser stimulation per point.
Latencies to move the leg after initiation of laser stimulation were compared using survival analysis for right-censored data [ 16] and the PROC LIFETEST in SAS 9.1 (SAS Inst. Inc., Cary, NC, USA).
Physiology and biophysics of laser stimulation.
Effect of laser stimulation of vM neurons on several wakeful behaviours.
Effect of laser stimulation on brain states in eYFP control mice.
Effect of laser stimulation of vM GABAergic neurons on the transition probability between each pair of brain states in ChR2 and eYFP control mice.
The changes of skin temperature during repeated laser stimulation were analysed in Experiment 2. To demonstrate the specificity of laser stimulation, reaction times to laser stimuli were analysed in Experiment 3.
To determine significant laser entrainment, a shuffling procedure was applied to spikes during individual laser cycles (20 ms of laser stimulation followed by 30 ms of no laser stimulation).
Some authors confirmed the presence of discrete vasoconstriction after noxious stimulation of latent trigger points [ 10, 11] and suggested the use of laser Doppler flowmetry rather than the less sensitive infrared thermovision (IRT) camera.
Use of laser photocoagulation decreased over time.
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