Sentence examples for use of laser microdissection from inspiring English sources
By use of laser microdissection pressure catapulting (LMPC) dysplastic cells in well defined lesions [18] could be isolated.
By use of laser microdissection pressure catapulting (LMPC) tumor cells without any contamination with normal epithelia, blood vessels, stromal cells and tumor necrosis could be isolated.
In conjunction with the use of laser microdissection (LMD) techniques, the second-gen NanoVelcro chip with a transparent polymer nanosubstrate was developed for single-CTC isolation.
Moreover, since prostate cancer is multifocal [ 30], the use of laser microdissection to isolate different clones present in the primary tumor will further refine our understanding of the clonal relationships of CTCs and their primary tumor focus of origin.
Limitations based on tumor heterogeneity and amplification of HER-2 in noninvasive cancer can be eliminated by the use of laser microdissection, although this seems to be impracticable for routine diagnosis [ 14].
For example, many groups have reported the use of laser microdissection (LM) to sample specific cell types from tissues (both fresh and formalin fixed) and subsequently analyze these samples using a variety of genomics and proteomics approaches.
Here, the use of laser-microdissection for the first time enabled the targeted harvest of those sites, where fungal hyphae first penetrate the root.
We here report the use of laser-microdissection of wax-embedded root tissues for a comprehensive inventory of gene expression during key developmental stages of the AM symbiosis, using roots of M. truncatula colonized with G. intraradices (recently renamed Rhizophagus irregularis[ 34]).
Using a combination of laser microdissection and quantitative PCR, Austbø et al. [8] found that the expression of PrP mRNA varied between tissue compartments in the ileal Peyer's patch of sheep, with highest levels of expression in the nerve rich compartments of the outer submucosa and muscle layers.
Additionally, 14-day-old live protonemata were used to obtain chloronemal and caulonemal tissues by means of laser microdissection.
The advent of laser microdissection has made this possible.
