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The use of human specimens in research has contributed to significant scientific and medical advancements.
O'Rourke (2007) has provided guidance on the use of human specimens and banking, which could be adapted to other forms of data banking.
We all know that the participation of human subjects and the use of human specimens are crucial to many types of basic, applied, pharmaceutical, and clinical research.
In all cases the collection, storage, distribution and use of human specimens and data were conducted in accordance with all applicable regulations including: 45 CFR Part 46: the FDA human subjects regulations 21 CFR Parts 50, 56, and 812: the Health Insurance Portability and Accountability Act (HIPAA) Privacy and Security Rules (45 CFR Parts 160 and 164): and any state and local laws.
There are also ethical issues accompanying the use of human specimens.
The Institutional Review Board at Kyushu University approved the use of human specimens for this study.
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The present study was designed to assess the expression of vWF using ex vivo analysis of human specimens of GC and adjacent non-tumor parenchymal tissues and to investigate the potential molecular mechanism of GC-related differential expression of vWF using in vitro analysis of human umbilical vein endothelial cells (HUVECs) exposed to VEGF.
Frozen sections (12 μm) of human specimens were prepared using a cryostat, post-fixed in ice-cold acetone for 15 min, and washed in 0.05% Tween (vol/vol -PBS.
It was covered by Human Subjects Protocol No. 990115 "Use of residual human specimens for the determination of frequency of genotypes or sub-types of pathogenic parasites", which was reviewed and approved by the Institutional Review Board of the Centers for Disease Control and Prevention CDCCenters for Disease Control and Prevention CDC
The use of these human specimens was approved by the Ethical Committee for Research on Human Being of the Geneva state.
Written informed consent for use of all human specimens in this study was obtained at the time of enrollment.
More suggestions(15)
use of surgical specimens
use of human shields
use of pooled specimens
use of fresh specimens
use of human antibiotics
use of miniaturized specimens
use of thick specimens
use of simple specimens
use of human participants
use of clinical specimens
use of human toxins
use of paired specimens
use of human structures
use of human cells
use of human rights
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