Sentence examples for use of historical control from inspiring English sources

Recommendations for the use of historical control data for the interpretation of avian reproduction studies are made.

Because neither active control nor placebo/dose control appeared to be acceptable alternatives for monotherapy studies in epilepsy, a new concept has been considered: the use of "historical control".

However, our results must be interpreted with caution given the well accepted limitations of use of historical control data and multiple non-randomized comparison groups.

Second, the use of historical control individuals limits our ability to draw strong conclusions.

The use of historical control data, the false-positive issue and the interpretation of negative trends are also discussed.

A statistical evaluation procedure for this assay is proposed herein, combining the use of historical control data and dose-response relationships.

This study, reporting on the first experience with a new technique at a single institution, is a controlled trial, but with the use of historical controls.

A concern about use of historical controls is lack of assurance that historical populations and newly recruited populations are similar.

The other studies, mostly small in size, used an open label design or were retrospective cohort studies with use of historical controls.

First, the use of historical controls may raise difficulties to ensure that obtained differences in outcome are related to the studied treatment.

The use of historical controls may be a viable alternative for comparing antifracture efficacy in osteoporosis fracture endpoint trials that do not have a placebo control group.