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It seems clear that the use of diverse cell systems in the different studies, with their particular features and maturation stages, is a key element probably involved or affecting the distinct behaviour of PLP during its transit to the myelin sheets.
As to molecular investigations based on the use of diverse cell culture models for kidney epithelial cells, there is some discrepancy between results obtained upon overexpression of PLCN-1 in two different kidney epithelial cell lines used.
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Long PINs show diverse polar localization in the PM of diverse cell types [ 6- 11].
The possible role of HLA-B27 in the invasion, intracellular survival or elimination of bacteria has been studied by investigators from different laboratories with different experimental settings with the use of diverse host cells and various triggering stimuli [ 30].
Recent genomic and expression profiling experiments have demonstrated the value of systematically analyzing such variability and it appears that a significant fraction of the complexity of specific human cancers can be captured using banks of genetically diverse cell lines [ 14, 15].
Many investigations have studied the use of diverse organic coatings as a way of optimizing the delivery of MNPs to or into cell.
- The use of diverse dissemination strategies.
Bone Morphogenetic Protein (BMP) signaling pathways are involved in differentiation of stem cells into diverse cell types, and thus BMPs can be used as main guidance molecules for in vitro differentiation of human stem cells.
Different cluster of differentiation (CD) antibodies, including CD3, CD4, CD8, CD16, CD19, CD25, CD45, CD127 are used to evaluate the number of diverse T-cell compartments, B- and NK-cells.
A major difference between these studies is the use of cell systems, which imply a diverse role for p53 in a cell type dependent manner.
Anand and his colleagues claim to have reproduced 99% of the brain's diverse cell types and genes.
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