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Importantly, this has been independently identified in two clinical cohorts, by the use of distinct methodologies, in Germany and the UK.
The lack of agreement between various studies exploring gender differences may reflect the use of distinct methodologies or the limitations in accuracy of our measurement method.
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These two biomarkers were derived using distinct methodologies: one using a linear risk-score analysis and the other using gradient-descent-based optimization.
The biomarker candidates need to be validated in a greater and statistically significant universe of individual samples using distinct methodologies such as Western blot, ELISA or single and multiple reaction monitoring (SRM or MRM).
(I count the telephone and online polls by Ipsos as separate surveys, since they use distinct methodologies).
Using two distinct methodologies, we next evaluated whether BM macrophages had a defect in neutrophil clearance in vivo (4), (45).
RNA-seq data for each tissue was aligned using two distinct methodologies – one for pseudogenes and one for real genes.
Additional studies of Wnt β-catenin signaling – using distinct methodologies – suggest a more complicated and context-dependent role for β-catenin.
The three types of NICE guidance are developed and updated using distinct methodologies.
We have demonstrated this by inhibiting BDNF action in the DG using two mechanistically distinct methodologies that impaired the discrimination of spatial representations only when the load for separation of representations was high.
Our results using ID Migraine™ were not much different from the other studies using distinct methodologies in the literature.
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