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This difference may be due to the use of different point mutants, since the mutation of K221 interferes with the binding of ATP.
How the use of different point values, or even the exclusion of points all together, might affect the processing strategies in which test-takers engage in the confidence-weighted testing format could well be a promising line for future research.
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The use of two different point of care coagulometers (CoaguChek® XS, Roche Diagnostics, Basel, Switzerland; INRatio®2, Alere Inc., San Diego, USA) with identical protocols within the NTS system allows direct comparison of their impact on patient outcomes.
Nevertheless, fairness hardly leads to a unique commitment: the same claims problem faced by two different agents may lead to the use of two different points of view (Moulin 1988; Schokkaert and Overlaet 1989; Young 1987, among others).
One could criticise the use of different end-points in the challenges.
The use of different cutoff points for IHC is of critical importance, as was shown by Lee et al (1995).
The use of different cutoff points for IHC is of critical importance, as shown by Lee et al (1995).
Moreover, the discrepancies in the results by study could also be due to use of different cut-points to define the status of HER expression or different methods to assay HER2.
There is also the risk of important bias when the choice of cutoff is data-driven and the use of different cutoff points across multiple studies hinders direct comparisons.
Although the use of different cut points for this wealth index was likely to influence results, it was generally a good way of distinguishing between socioeconomic layers within a population in the absence of reliable information on income or expenditures.
Evidence however, has been inconclusive owing to the lack of standardization in survey instruments and the use of different cutoff points for screening tools in determining clinically significant symptomatology [ 8].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com