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Like so many sciences, molecular biology and genetics are being transformed by the use of computational tools.
Accordingly, the educational strategies and curricula can be redesigned in order to integrate courses more efficiently both horizontally and vertically, and upgrade the use of computational tools.
Given the tremendous growth of bioactivity databases, the use of computational tools to predict protein targets of small molecules has been gaining importance in recent years.
Alongside classical experiments for assessing toxicity, the use of computational tools is gaining more and more interest in the scientific community and in the industrial world as accompaniment to or replacement of existing techniques.
The development and use of computational tools can benefit from the many collaboration features available on Vhub including discussion panels, internal messaging, wish lists, wiki pages, and Q&A sections.
In some cases, these problems also occur due to the application of inaccurate empirical dimensioning methods, without the wide use of computational tools, which would yield a more accurate structural analysis results.
Similar(41)
Bioinformatics is being increasingly used to support target validation by providing functionally predictive information mined from databases and experimental datasets using a variety of computational tools.
Using a range of computational tools and resources, we have compiled information on all experimentally annotated changes in enzyme function within 379 structurally defined protein domain superfamilies, linking the changes observed in functions during evolution to changes in reaction chemistry.
We comparatively studied the extent of conjoined genes in thirteen genomes by analyzing the public databases of expressed sequence tags and mRNA sequences using a set of computational tools designed to identify conjoined genes on the same DNA strand or opposite DNA strands of the same genomic locus.
High level of intrinsic disorder and a substantial number of potential interaction sites were also found using a set of computational tools.
The large-scale analysis of the abundance of intrinsic disorder in transcripts of the various disease-related genes was performed using a set of computational tools described in a previous section [ 106].
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