Other risk factors that have been proposed include longevity, metabolic syndromes [ 132], and use of certain pharmacologic agents [ 133].
Since disease site confounded with the use of certain cytotoxic agents, a separate stepwise logistic regression model without disease site was used for further analysis.
Apart from inactivity by mechanical ventilation, other factors including inflammation, malnutrition, the use of certain pharmacological agents, and the existence of neuromuscular syndromes prior to ICU admission have been reported to influence diaphragm dysfunction as well [ 13].
Therefore, high-throughput methods for screening of candidate homoeologous gene deletions are needed for application to wheat populations generated by the use of certain mutagenic agents (e.g. heavy ion irradiation) that frequently generate whole-gene deletions.
Several pilot studies concerning the use of certain chemotherapeutic agents including cisplatin for haemodialysis patients, however, have shown the feasibility of such attempts by reducing the doses of the agents (Ayabe et al, 1989; Umeki et al, 1990; Ono et al, 1992).
Consequently, the use of certain antimicrobial agents (avoparcin, tylosin, spiramycin, bacitracin and virginiamycin) as animal growth promoters have been banned by the European Union in 2001, and the Health Ministries in the European Union have subsequently agreed to discontinue the use of all antimicrobial growth promoters.
Diabetic patients with CVD may have conditions (e.g., congestive heart failure) that prevent the use of certain anti-hyperglycemic agents.
One of the most difficult issues in this patient population is that loss of renal function results in marked metabolic and fluid disturbances that may preclude the safe use of certain classes of oral antidiabetic agents.
For instance, we can utilize oxidative stress scavengers to inhibit transdifferentiation, apply oxidative stress-inducing agents to ROS sensitive tumors, and use certain agents to limit the process of EMT and cancer stem cell differentiation.
The use of certain pesticides is controversial.
