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Use of bone surface models would be a further advancement of the model-based method by decreasing complications arising from marker insertion.
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This labeling allowed for evaluation of bone surface (BS), single labeled surface (sLS) and double labeled surface (dLS).
Quantitative measurements of bone surface and bone volume were calculated for each metatarsal bone.
The indices of static resorption included eroded surface and osteoclast surface (both in % of bone surface).
The percentage of bone surface displaying resorption was assessed blind by a single researcher (HH), across the entire surface of each bone slice using reflected light microscopy at a magnification of 40×.
Absorbable collagen membrane could control the texture of bone surface.
In contrast, osteoblasts at the cortical bone surface covered a significantly greater amount of bone surface (21%) than osteoclasts (7%).
For determination of common bone parameters, such as quantitation of cell types, determination of bone surfaces, and mineral apposition rate, the slides were evaluated with use of the Bioquant Morphometric System (Bioquant Image Analysis Corp., Nashville, TN).
The aim of this pilot investigation was to assess the feasibility of a "completely markerless" model-based RSA in detecting migration of an implant using bone surface models instead of bone markers.
Furthermore, we validated this bone imaging technique successfully by using bone surface μCT data.
This means that F-NaF can be used not only for the common measurement of bone mineral deposition but also for visualization of osteolytic increases of exposed bone surface, such as in the context of musculoskeletal autoimmune disease [ 10].
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