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Fears of bovine spongiform encephalopathy, or mad cow disease, have led to a ban on the use of bone meal in European cow diets because the ingredient can spread the disease.
Because there are no early warning signs, awareness of the risk factors and the use of bone density tests are critical to catching it early and preventing further bone loss.
The use of bone cement is widespread in orthopaedic surgery.
The use of bone grafts in the management of nonunion cases is well accepted.
The use of bone mass measurements for prognosis depends upon the accuracy.
Use of bone morphogenetic proteins has been associated with increased incidence of seroma formation [21].
Another significant cause of stem failure was detected with the use of bone cement.
Many of these procedures involve the use of bone graft substitutes.
The use of bone marrow mononuclear cells (BM-MNCs) has achieved great outcomes in clinical practice.
Moreover, the mechanical strength provided by this construct does not necessarily require the use of bone grafting.
Surgeons therefore should consider using this technique in order to minimize the use of bone substitutes without additional harvesting morbidity.
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