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Because the use of a third dose of MMR vaccine is not recommended by ACIP for PEP, a protocol was submitted and approved by the US Centers for Disease Control and Prevention and New York State Institutional Review Boards.
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Arkansas, which had a large outbreak last year that started in a community of Marshall Islanders, used a third dose of the MMR vaccine in schools to control further transmission.
Arkansas has used a third dose of the MMR vaccine in schools to control further transmission.
Other studies, however, using a third dose at the end of the day did find a greater sleep-onset delay in children treated with stimulants compared to untreated subjects [ 7, 137].
Routine use of a third vaccine dose at 18 years of age, or booster dosing throughout adulthood, may be a strategy to prevent mumps re-emergence and should be assessed in clinical trials.
A recent study suggested that use of a third MMR dose might be an effective control measure in certain outbreak situations (27 ).
The model used in this analysis suggested that transitioning from MMR + V to MMRV may substantially reduce the number of hospitalisation days, despite the observed increased risk of FC when MMRV was used as a first dose of measles-containing vaccine.
MMRV use instead of MMR + V can substantially reduce the number of hospitalisation days, despite increased FC risk when MMRV is used as a first dose of measles-containing vaccine.
These observations suggest that both MMRV vaccines, when used as a first dose of measles-containing vaccine, are associated with an increased risk of FC [ 17].
37 39 Notably, unlike previous studies conducted in other countries, 28 30 33 this study did not demonstrate any difference in fever rates between MMRV and MMR when used as a first dose of measles-containing vaccine.
Attempts to avoid recurrence with triptans, either by using a second dose of sumatriptan or by using triptans with longer elimination half-lives, have largely been unsuccessful.
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