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The use of a targeted and potent repressor domain increases the efficiency of transcriptional repression of cancer-causing genes.
The use of a targeted drug delivery system containing TIMPs or other molecules to induce an environment favourable to hyaline cartilage regeneration with the possible addition of a systemic agent may also play a role.
The use of a targeted thermal 'trigger' such as photon activation (i.e., NIR light) or radiofrequency electric fields could allow these SGSs to release their cargo into the cells upon irradiation by a stimuli.
These examples show that a PLS system's cost-effectiveness depends on its site-specific characteristics, including location, installation cost and performance, thus affirming the use of a targeted approach to DR design and implementation.
The use of a targeted drug carrier (e.g., a liposome) to release chemotherapeutic drugs specifically in the neighborhood of EGF-overexpressing tumors has the potential to achieve the treatment ideality of maximal efficacy and maximal specificity [11].
Based on these findings we anticipate that the combination of composting conditions (30 55°C, pH 6 8), use of a targeted feedstock and codon optimization of identified candidate enzymes to improve heterologous expression will supply physiologically versatile and feedstock-specific enzymes applicable to emerging pretreatment practices such as ionic-liquid pretreatment [30].
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In this study, we explored the ability of biomaterial-mediated intrinsic targeting of primary human brain cancer cells over primary human neural progenitor cells without the use of a targeting ligand or transcriptional targeting.
The use of a lower, targeted vancomycin dose through IORA optimizes timing of administration and reduces the risk of such systemic toxic effects.
The high proportion of significantly changing genes reflects our generation and use of a microarray targeted to dormancy processes in Ribes.
It is important to recognize the limitations of our study, most notably small sample size and use of a hotspot targeted gene panel.
The use of a modified targeted intentional rounding tool by the nursing shift leader can help ensure that best practice guidelines are adhered to.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com