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Model-based optimization reveals the beneficial effect of the use of a stepwise temperature program, as confirmed experimentally via a lowering of the dispersity from a conversion of 0.3 on due to a suppression of thermal initiation and chain transfer to dimer.
Vo2max was indirectly estimated by use of a stepwise work capacity on a stationary exercise cycle (Monark Ergomedic 839E, Sweden).
In particular, we propose use of a stepwise hierarchical approach and novel ancestry panel tools in AM analysis projects where ERR or sample size may be limiting.
This problem is avoided in GEMOT by the use of a stepwise heuristic approach that drastically reduces the search space and allows scalability to large networks.
With the use of a stepwise forward analysis that included all predictors, first baseline HbA1c and then only peroneal MCV at baseline entered significantly (R = 61%).
The FDA intends to use a 'risk-based, totality-of-the-evidence' approach for biosimilar application reviews and recommends use of a stepwise approach to demonstrate biosimilarity 21.
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The same selection of the best predictors was obtained with the use of a forward stepwise procedure, for details see the Electronic Supplementary Material.
Those factors with P < 0.25 in univariate analysis were then analyzed by multivariate analysis with use of a forward stepwise selection strategy.
The final set of significant factors associated with awareness was identified through the use of a forward stepwise selection procedure with entry probability of 0.05 and removal probability of 0.10.
Relative risks were estimated by exp, where β is the hazard coefficient for the variable of interest in a Cox's proportional hazards regression model [ 22] with the maximum likelihood ratio method and the use of a backward stepwise elimination procedure in analyses adjusted for age only, and in a final model including also other potentially relevant variables.
They can be minimised through the use of an appropriate stepwise dosing regimen and careful choice of diet.
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