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Patients who receive acupuncture may be able to use lower doses of pain medications.
Interestingly, despite the lack of published evidence of a gender difference in MMC HIPEC PK, some well-established HIPEC programs use lower doses of chemotherapy in women.
10 It is conceivable that the use of azathioprine or MMF allows clinicians to use lower doses of other diabetogenic immunosuppressive medications.
As an alternative to administering prophylactic steroids to reduce the degree of fluid retention, Japanese studies have tended to use lower doses of docetaxel than those used in European and American trials.
Additionally, increased use of proton pump inhibitors, widespread efforts to use lower doses of NSAIDs, increased use of safer NSAIDs, and improved treatment of acute ulcer bleeding have also contributed to lower mortality rates [ 37- 40].
Synergy between PNP-GDEPT and docetaxel and/or carboplatin has important clinical implications; in particular, the ability to use lower doses of each modality should translate in the clinic to decreased side effects and an improved quality of life.
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Additional studies investigating the pharmacokinetic and pharmacodynamic dose-response characteristics of glargine using lower doses of the insulin in less obese individuals would also be useful.
He added that studies were already under way to see if the same results could be obtained using lower doses of radiation.
Therefore, combination therapies with ASA, APAP and caffeine were developed to provide superior efficacy using lower doses of analgesics compared with therapeutic doses of monotherapy [8, 9].
The beneficial effects on pain are in agreement with other studies; the reduction in headache pain was greater with the triple combination vs. monotherapy, using lower doses of analgesic [9, 15].
Breast cancer has long been linked to hormonal contraception — but the prevailing wisdom among young women was that modern birth control, which uses lower doses of estrogen, is now much safer than the birth control past generations of women used.
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