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For example, the statement in the ICHS6, "for those biopharmaceuticals intended for chronic use indications, studies of 6 months duration have generally been appropriate…"; is this still relevant?
This single-center retrospective study was designed to assess the use (indications, efficacy, and side effects) of anti-TNF-α agents in noninfectious uveitis.
The known hazards of MRI unsafe CIEDs are described, followed by guidelines on safe use, indications and limitations of imaging patients with MR conditional CIEDs, including a brief pictorial essay of the radiographic features of these devices.
Between-group differences in sex ratio, anti-ulcer drug use, indications for LDA therapy, and tertile CE scores were analyzed by Fisher's exact test.
The rationale use of these agents is hindered by a lack of data concerning drug scheduling, duration of use, indications for initiation and cessation [ 9].
Patients on herbal remedies were asked about the history of herbal use, indications, frequency and if their healthcare providers were aware of this.
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Outside the controlled environment of clinical trials, several variables may affect the pharmacodynamics of a particular drug, including dosage, duration of use, indication, comorbidities, and use of concomitant medications.
Firstly, we did not use indication specific dose estimates for fluoroscopy and radiography.
Consequently, we were unable to use indication to further restrict our study cohort.
Drug use indication bias and prevalent user bias may be possible when assessing these associations using cross-sectional health survey data (40).
Biases that can result in confounding effects include drug use indication bias, prevalent user bias, detection bias, and time-related biases.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com